Assessment of the 2006 revised antiphospholipid syndrome classification criteria

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Comparison of the 1999 Sapporo and 2006 revised criteria for the classification of the antiphospholipid syndrome.

OBJECTIVES The 2006 revised criteria for antiphospholipid syndrome (APS) provide a new classification challenge, and studies validating the updated criteria against the older ones are still scanty. We compared the 1999 preliminary with the 2006 revised classification criteria for APS, and evaluated if the revised criteria provide an added value over the original ones. METHODS A laboratory-bas...

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Critical Update of the Antiphospholipid Syndrome Criteria

Diagnosis of Antiphospholipid Syndrome (APS) is made when vascular thrombosis or pregnancy morbidity occur in patients with circulating antiphospholipid antibodies [lupus anticoagulant (LA) and/or IgG/IgM anticardiolipin (aCL) and/or IgG/IgM anti2glycoprotein I (a 2GPI) antibodies]. Although each test may identify different autoantibodies, a single positive test makes the diagnosis possible whe...

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Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome.

OBJECTIVE To describe the characteristics of patients with catastrophic antiphospholipid syndrome (APS) included in the International Registry of patients with this condition (CAPS registry) and to analyse the value of the recently proposed preliminary criteria for the classification of catastrophic APS. METHODS A review of the first 220 patients included in the website based CAPS registry wa...

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Diagnosis and classification of the antiphospholipid syndrome.

The antiphospholipid syndrome (APS) is defined by the occurrence of venous and arterial thromboses, often multiple, and recurrent fetal losses, frequently accompanied by a moderate thrombocytopenia, in the presence of antiphospholipid antibodies (aPL). Some estimates indicate that the incidence of the APS is around 5 new cases per 100,000 persons per year and the prevalence around 40-50 cases p...

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International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).

New clinical, laboratory and experimental insights, since the 1999 publication of the Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been addressed at a workshop in Sydney, Australia, before the Eleventh International Congress on antiphospholipid antibodies. In this document, we appraise the existing evidence on clinical and laboratory features of APS addre...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2007

ISSN: 0003-4967

DOI: 10.1136/ard.2006.067314